NMR A to Z Course
Prof. Gary Martin
December 2, 4 and 6, 2024
11:00-12:00 am (Brasília time)
PROGRAM
December 2nd: NMR A to Z presentation
- Begins with simple 1D 1H and 13C spectral considerations.
- Progresses to the standard suite of 2D experiments routinely employed (by me anyway) for structure elucidation including COSY, HSQC, HMBC, and HSQC-TOCSY
- Introduces the family of ADEQUATE experiments, anisotropic NMR methods, and wraps up with i-HMBC that we developed just over a year ago that differentiated 2JCH from 3JCH HMBC correlations on the basis of sub-ppb (PPB not typo) isotope shifts.
December 4th: Florfenicol - Small Drug Molecule Lecture
- Walks students through the basic suite of 1D and 2D NMR techniques.
- Introduces the aspects of multiple halogenation (-Cl and -F) on chemical shift and using heteronuclear JCF coupling as assignment critera.
December 6th: Platensimycin - Complex Natural Product Characterization Lecture
- When platensimycin was first isolated and characterized it was necessary to utilize multiple solvent techniques due to proton overlap.
- Structural characterization using modern techniques including IDR-HSQC-TOCSY, 1,1- and 1,n-ADEQUATE, and i-HMBC will be described.
REGISTRATION:
- Registration: 01 to November 25, 2024.
- Payment: Credit Card or Bank slip.
Price table
CERTIFICATES:
- All registered participants will receive certificates.
