Coffee break + posters

Type:

Poster

Category:

Poster

Place:

Tucuns/Tartaruga

Date and time:

13:30 to 14:15 on 11/05/2025

🚨 Each poster session is scheduled over two days to maximize interaction:

➡️ Posters presented on the afternoon of November 4th will remain available on the morning of November 5th.

➡️ Similarly, posters presented on the afternoon of November 5th will remain available on the morning of November 6th.

Share your questions or ideas about this activity!

Papers

Poster - 210281

Targeting the Cellular Prion Protein for Synaptic Function and Network Dynamics

Anna Burato, Lucia Zanetti, Alessio Di Clemente, Valentino Panico, Camilla Lodetti, Beatrice Pastore, Marco Zattoni, Luigi Celauro, Katja Reinhard, Michele Giugliano, Giuseppe Legname,

Poster - 210194

TARGETING α-SYNUCLEIN AGGREGATION VIA hHEP1-MEDIATED PHASE SEPARATION: MECHANISTIC INSIGHTS INTO THE COCHAPERONE–α-SYNUCLEIN INTERACTION

Antonio Silva, Beatriz Ladeira, Noeli S M Silva, Mariana Tavares, Julio C Borges, Debora Foguel,

Poster - 210230

Divalent Metal Ions Modulation of the Prion Protein Biomolecular Condensate Formation and Aggregation

Mariana J. Do-Amaral, Aline Passos, Satabdee Mohapatra, Letícia Oliveira, Taiana S. L. Da Silva, Renato S. Carvalho, Marcius Almeida, Anderson Pinheiro, Susanne Wegmann, Yraima Cordeiro,

Poster - 210259

“Procrustean bed”: Preliminary modelling of the very first steps of PrPC conversion to PrPSc through Molecular Dynamics

JESUS REQUENA, Iria Díaz Arias, Emiliano Biasini, Marta Rigoli,

Poster - 210190

Structural variation in amyloid beta and tau filaments from distinct Alzheimer's disease clinical subtypes

Diego Caron, John Collinge, Wenjuan Zhang,

Poster - 210169

Investigating the role of the cellular prion protein and its partner STIP1 in neurodevelopment

Camila Fernandes, Lucas Prestes Helzel, MARILENE HOHMUTH LOPES,

Poster - 210167

Structural and functional characterization of the TCF25/Rqc1 protein and its role in neuronal development

Otávio Augusto Leitão dos Santos, Dayana Carolina Souza de Oliveira Melo, Raissa da Silva Santos, Fernando Palhano,

Poster - 210212

PrPC and its ligands in primary cilia dynamics in glioblastoma models

Isabella de Sousa Nóbrega, Maria Isabel Melo-Escobar, Bárbara Paranhos Coelho, Breno Pereira de Sousa, Giovanni Cangiano, MARILENE HOHMUTH LOPES,

Poster - 210152

EXPRESSION AND PURIFICATION OF AMYLOID-BETA PEPTIDE 1-40: AN IN-DEPTH ANALYSIS FOR ISOLATION OF ITS MONOMERIC STATE

Maria Eduarda Roncorroni Porto, Gustavo Bacelar de Mello Alves, Mônica Santos de Freitas,

Poster - 210251

Polymorphic alpha-Synuclein Aggregates Mediate Differential Cellular Toxicity Profiles

SHUBHAM KUNDU, Nakul C Maiti*,

Poster - 210154

Conformation-specific antibody Fab YEG Sc-G1 isolates an infectious ß-solenoid conformer of PrPSc

Isa Dzhabrailov, Vineet Rathod, Brian Tancowny, Lyudmyla Dorosh, Maria Stepanova, Holger Wille,

Poster - 210213

Cellular prion protein drives mesenchymal identity and microenvironment interaction in glioblastoma

Maria Clara da Silva Souza, Camila Fernandes, Raghavendra Vadla, Abhinaba Banerjee, Yohei Miyaken, Shamini Ayyadhury, Barbara Coelho, Nidhi Nathwani, Breno Sousa, Frank Furnari, MARILENE HOHMUTH LOPES,

Poster - 210149

Novel polymorphisms and genetic studies of the shadow of prion protein gene (SPRN) in pheasants

Da-In Choi, Byung-Hoon Jeong,

Poster - 210151

BIOACTIVE PROCYANIDINS FROM AÇAÍ SEED: EVALUATION OF THE ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY OF THE EXTRACT AND ITS FRACTIONS WITH DIFFERENT DEGREES OF POLYMERIZATION

Marcos Filipe Muniz Faria, Debora Foguel, Ariele da Silva Martins,

Poster - 210153

In vitro evaluation of the anti-prion activity of hydroalcoholic extracts from Moringa oleífera Lamark (Moringaceae)

Manuela Amaral do Nascimento,

Poster - 210155

New cytotoxic menadione derivatives modulate different mutant p53 amyloid fibrils

Marcelly Muxfeldt, Acácio de Souza, Thaís Barreto, David da Rocha, Yraima Cordeiro, Vitor Ferreira, Jerson L. Silva, Luciana Pereira Rangel,

Poster - 210156

The Therapeutic Potential of the Menadione Derivative RCT-13 in Burkitt Lymphoma

IGOR DA SILVA DE ARAUJO, Julia Quarti, Luciana Pereira Rangel, TUANE VIEIRA, Jerson L. Silva,

Poster - 210158

IN SILICO ANALYSIS OF THE INTERACTION OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS WITH TRANSTHYRETIN

Letícia Martins, Lucas Martins, Isabella Guedes, Debora Foguel,

Poster - 210179

Evaluation of anti-prion compounds targeting CWD using the RT-QuIC assay

Yu-Ran Lee, Hoo-Chang Park, Hae-Eun Kang, Hyun-Joo Sohn,

Poster - 210160

EFFECT OF AMAZONIAN Banisteriopsis caapi EXTRACT ON THE DISAGGREGATION OF THE AMYLOIDOGENIC PROTEIN α-SYNUCLEIN INVOLVED IN PARKINSON´S DISEASE

Vinicius Benjamim Canetti, Lucas Martins, Debora Foguel,

Poster - 210161

Ayahuasca alkaloids as novel inhibitors of α-synuclein amyloid fibril formation

Lucas Martins, Vinicius Benjamim Canetti, Israel Rodrigues, Mariana Azevedo, Debora Foguel,

Poster - 210163

Mutant p53 Aggregation in Burkitt’s Lymphoma: A Potential Therapeutic Target of Piperine in Association with PRIMA-1

Julia Quarti, IGOR DA SILVA DE ARAUJO, Rickson Ribeiro, Giulia Ferretti, Juliana Maria Motta, Morgana Castelo Branco, Luciana Pereira Rangel, TUANE VIEIRA, Jerson Lima,

Poster - 210173

Virtual Screening of Brazilian Biodiversity-Derived Natural Products Targeting α-synuclein Prion-like Aggregation

Priscila Baltazar Gonçalves, Nilton Silva Júnior, Rafaela Moreira Lazaroni, Yraima Cordeiro,

Poster - 210174

TWO UNEXPECTED CASES OF VARIABLY PROTEASE SENSITIVE PRIONOPATHY PRESENTING WITH A MOTOR NEURON/FRONTOTEMPORAL DEMENTIA SYNDROME IN A SMALL REGION IN NORTHERN SPAIN IDENTIFIED WITHIN ONE YEAR

María Elena Erro, Ivonne Jericó, María Victoria Zelaya, Cristina Caballero, Fermín García-Amigot, Javier Sánchez Ruiz de Gordoa, Anika Simonovska Serra, Isidre Ferrer, Joaquín Castilla, Ellen Gelpi,

Poster - 210180

Strain-distinct α-Synuclein and Tau Cross-seeding Uncovered by Correlative Approach with Optical Photothermal Infrared Sub-micron Imaging

Xiaoni Zhan, Wen Li, Eric Hatterer, Jean-Philippe Courade, Kristin Piché, Oxana Klementieva, Jia-Yi Li,

Poster - 210172

Identification of Camel Prion Disease in Tunisia: evidence of an emerging prion disease in North Africa

Abdelkader Amara, Michele Angelo Di Bari, Rihab Andolsi, Kéfia Elmhatli, Atef Malek, Rosalia Bruno, Barbara Chiappini, Ilaria Vanni, Elena Esposito, Geraldina Riccardi, Boubaker Ben Smida, Haykel Kessa, Walid Chandoul, Malek Zrelli, Obaid Allah Ben Abid, Stefano Marcon, Romolo Nonno, Umberto Agrimi, Gabriele Vaccari, Laura Pirisinu,

Poster - 210177

Application of Real-Time Quaking-Induced Conversion assay to investigate the presence of pathological prion protein in extra-neural tissues of cattle with natural Low BSE.

Maria Mazza, Christina D. Orrù, Alessandra Favole, Luana Dell'Atti, Cristiano Corona, Cristina Casalone, Pier Luigi Acutis, Elena Bozzetta,

Poster - 210175

Ribosomal Proteins Form Aggregates with Amyloid Properties in Yeast and Human Cells

Yulia Andreychuk, Veronika Lashkul, Marina Ptushkina, Olja Mijanovic, Ekaterina Nikitina, Anna Aksenova, Yury Chernoff, Aleksandr Rubel,

Poster - 210178

Intervening in functional amyloid assembly/disassembly to overcome biofilm-driven microbial resistance

Ariane Duarte Rosse, Luís Mendes,

Poster - 210164

Targeting the PrPC–CD44 axis: insights into protein trafficking in glioblastoma stem-like Cells

Rodrigo Nunes, Mariana Prado, Maria Clara da Silva Souza, Barbara Coelho, Maria Isabel Melo-Escobar, Mario Cruz, Tiago Santos, Claudia Angeli, Giuseppe Palmisano, MARILENE HOHMUTH LOPES,

Poster - 210181

Uncovering neurotoxic and neuroprotective mechanisms driven by PrPC-ligand interactions

Aiman Riaz Mirza, Irina Zemlyankina, Sabine Gilch,

Poster - 210182

Phosphatidic Acid-Mediated Prion Aggregates Disrupt Mitochondrial Activity

Rayanne Moura-do-Nascimento, Gabriela Assis-de-Lemos, Antonio Galina, TUANE VIEIRA,

Poster - 210184

Assessing the effect of GBA1 gain-of-function mutations on neuronal organelle homeostasis and on α-synuclein accumulation and spreading

Manuel Flores León, Tiago Outeiro,

Poster - 210183

Characterizing subclinical infection and strain evolution in gene-targeted mouse models of CWD (Authors: Kristen Gregg, Maria Arifin, Anja Itum, Raychal Ng, Samia Hannaoui, Sabine Gilch)

Kristen Gregg, Maria Arifin, Anja Itum, Raychal Ng, SAMIA HANNAOUI, Sabine Gilch,

Poster - 210185

Standardizing Statistical Tests for CWD Detection with “Tricky” samples for RT-QuIC

Madison Davis, Jennifer Hoy-Peterson, Brock Geary, Roderick Gagne, Michelle Gibison,

Poster - 210267

Trehalose protects against glycation and aggregation of SOD1

Gabriel Freitas de Souza, Cristian Follmer, Elis Eleutherio,

Poster - 210206

High-resolution characterization of the formation of prion oligomers driving the initial phases of pathogenic conversion

Roberto Fattorusso, Nataliia Ventserova, Luigi Celauro, Gaetano Malgieri, Gianluca D'Abrosca, Carla Isernia, Giuseppe Legname,

Poster - 210171

Exploring the UPR pathway effects in synaptic activity of cortical neurons, under the context of prion disease

Santiago Esteban Quintana Herrera, Valentina Paz De La Fuente Vega, Carla Torres-Fuentes, Tamara Fernanda Cáceres Palma, Ninoschka Troncoso, Paul Soto Ortega, David Flaig Lobos, Alejandra Fuentes-Garrido, Human Rezaei, Gustavo Moraga Cid, Carola Muñoz Montesino,

Poster - 210205

Impact of Neurodevelopmental Disorder-Associated Mutations on DDX3X Structure and Oligomerization

Ivan Rosa e Silva, Felipe Zanghelini Benevenutti, Paula Favoretti Vital do Prado, Renata Oliveira, Barbara Mendes De Souza Pereira, Mauricio Luis Sforça, Juliana Helena Costa Smetana, Andrey Fabricio Ziem Nascimento, Juliana Ferreira de Oliveira,

Poster - 210203

Dissecting the Role of PrPc’s Partner Stip1 in Early Embryogenesis via Wnt Signaling

Samuel Ribeiro Soares, Marilene Lopes, Camila Fernandes,

Poster - 210293

3D atomic structure reveals evolution of prions in templated amplification in vitro

Adam Wenborn, Ioanna Christina Chatzitheodosiou, Kezia Jack, Jonathan Wadsworth, Graham Jackson, Szymon Manka, Jan Bieschke,

Poster - 210176

Engineering Protective PrPC Variants to Suppress and Reverse Prion Infection in Cell Models

May Liew, Parineeta Arora, Mark Batchelor, Jan Bieschke, Parmjit Jat, John Collinge,

Poster - 210249

Tracking Prion Evolution as It Happens

Ioanna Christina Chatzitheodosiou, Leyang Lucas Chen, Mark Batchelor, Jan Bieschke,

Poster - 210168

STI1 Phase Separates and Modulates PrP Droplet Behavior

Maria Heloisa Freire, Aline Passos, Mariana Juliani Do Amaral, Rafael Linden, Yraima Cordeiro,

Poster - 210198

Molecular Mechanisms Underlying Mutant p53 Gain of Function in Glioblastoma

Michelle Mota,

Poster - 210227

How prion fibrils marry conserved architecture with structural diversity and why it matters

Szymon Manka,

Poster - 210263

Cryo-ET reveals subcellular pathology in prion-infected neurons

Thomas Trainer, Adam Wenborn, Jonathan D.F. Wadsworth, Szymon W. Manka,

Poster - 210148

Total-PrP Profiles in Blood and CSF: Insights into Pre-symptomatic and Symptomatic Prion Disease

Ines Laginha, Matthias Schmitz, Tayyaba Saleem, Angela Da Silva Correia, Susana Correia, Peter Hermann, Dana Žáková, INGA ZERR,

Poster - 210271

Data-driven sequencing of clinical and biological markers in prodromal stages of inherited prion disease

Leah Holm-Mercer, Edgar Chan, Harpreet Hyare, Lee Darwent, Thomas Coysh, Akin Nihat, Melissa Ng, John Collinge, Simon Mead, Tze How Mok,

Poster - 210234

Detection of Alpha-Synuclein Seeding Activity in Tear Fluid as a Non-Invasive Biomarker for Parkinson’s Disease

Sezgi Canaslan, Matthias Schmitz, Fabian Maas, Peter Hermann, Susana Correia, Wiebke Möbius, Christoph van Riesen, INGA ZERR,

Poster - 210238

Distinguishing synucleinopathies through characterization of skin α-synuclein RT-QuIC end-products

WEN-QUAN ZOU,

Poster - 210241

Profiling Tear Fluid in Prion Disease: A Pilot Proteomics Study

Angela Da Silva Correia, Susana Da Silva Correia, Tayyaba Saleem, Matthias Schmitz, INGA ZERR,

Poster - 210252

Longitudinal plasma biomarker profiling in fatal familial insomnia

Roberto Chiesa, Giada Lavigna, Monica Favagrossa, Eleonora Busani, Ilaria Raimondi, Laura Pasetto, Ignazio Roiter, Vladimiro Artuso, Joaquín Castilla, Izaro Kortazar-Zubizarreta, Gianluigi Forloni, Valentina Bonetto,

Poster - 210253

Regional Variations in Seeding Activity, Phosphorylation, and Protein Levels of Tau in Alzheimer's Disease Brain

yang yirong, Guan Huiying, Wu Hailun, Xiong Ying, You Wuxin, Hengxu Mao, Xu Can, yaoyun kuang, Yi Hancun, Li Mengting, Gu Yuejun, Huang Pengcheng, Yan Xiao-xing, Ansgar Potesch, Shi Yang, Xu PingYi, Huang Yue, hong daojun, WEN-QUAN ZOU,

Poster - 210268

Strain-Specific Prion Seeding Dynamics and Proteomic Changes in Human CJD: Toward Early Diagnosis

Saima Zafar, Neelam Younas, Matthias Schmitz, Olivier Andréoletti, INGA ZERR,

Poster - 210272

Systematic Plasma Biomarker Signatures in preclinical and clinical Creutzfeldt-Jakob Disease

Liyong Wu,

Poster - 210220

Rapid and sensitive determination of residual prion infectivity from prion decontaminated surfaces

Sara Simmons, Jason Bartz, Qi Yuan, Vivianne Payne, Jay Hrdlicka, Jack Taylor,

Poster - 210173

Disease-Specific Hypometabolic Epicenters in Prion diseases and their Clinical Implications

Min Chu, Liyong Wu,

Poster - 210284

PROGNOSTIC VALUE OF CSF TOTAL TAU PROTEIN IN PATIENTS WITH CREUTZFELDT-JAKOB'S DISEASE

Yacov Balash, Esther Kahana, Hanna Rosenmann, Nurit Omer, Amos D. Korczyn,

Poster - 210289

Detection of skin α-synuclein using RT-QuIC as a diagnostic biomarker for Parkinson’s disease in the Chinese population

Haiyang Luo,

Poster - 210291

Advancing Parkinson's Disease Diagnosis: Nano-QuIC Platform for Serum α-Synuclein Detection

Suying Duan, Haiyang Luo, Yuming Xu,

Poster - 210295

An ultrasensitive quaking-induced conversion assay for all forms of sporadic and inherited human prion diseases

Stephanie Booth, Jennifer Myskiw, Rebecca Fox, Dominic Kielich, Lise Lamoureux, Olivia Ferriera, Jessy Slota, Ben Bailey-Elkin,

Poster - 210298

Cerebrospinal Fluid Biomarkers in Genetic Creutzfeldt-Jakob Disease: A Slovak Cohort Study

Dana Žáková, Silvia Koščová, Katarína Melicherová, Alžbeta Janáková, Zuzana Szarvasová, Dana Kosorinová, Martin Štelzer,

Poster - 210228

Serum α-Synuclein Seeding Amplification Assay: A Non-Invasive Biomarker for Early Detection of Parkinson's Disease

yaoyun kuang, Hengxu Mao, Wei Dai, Pingyi Xu,

Poster - 210245

An optimized protocol for PrPSc detection in CSF and tear fluid

Susana Margarida Da Silva Correia, Matthias Schmitz, Peter Hermann, Stefan Goebel, Paul Lingor, Fabian Maas, Anna-Lisa Fischer, Sezgi Canaslan, Angela Da Silva Correia, INGA ZERR,

Poster - 210211

Extracellular vesicle microRNAs from iPSC-derived dopaminergic neurons as biomarkers in Prion and Parkinson’s Diseases.

Martha Liliana Medina, Lilian Cruz, MARILENE HOHMUTH LOPES,

Poster - 210188

Identification and validation of novel blood-based biomarkers for monitoring progression of prion disease

E Fiona Houston, M Khalid F Salamat, Ciara A Farren, Samantha L Eaton, Dominic Kurian, Andrew C Gill,

Poster - 210207

Mapping preclinical neurodegeneration: A window into genetic prion disease progression

Neelam Younas, Abrar Younas, Joaquín Castilla, Hasier Erana, Izaro Kortazar-Zubizarreta, Roberto Chiesa, Peter Hermann, Saima Zafar, Susana Correia, Angela Da Silva Correia, Matthias Schmitz, Inga Zerr,

Poster - 210199

Rapidly progressive dementia besides prion diseases: a multicentric tertiary hospital study

Eduardo de Novaes Costa Bergamaschi, Adaucto Wanderley da Nóbrega Junior, Edson Pillotto Duarte, Matheus Souza Steglich, Manuela Aparecida Kloeppel, Gabriel Martins Rodrigues, Iara de Sousa Coelho, Myllan Eiroa Feitosa, Katia Lin,

Poster - 210215

Development of a single-allele sequencing tool to study of PRNP variants in Chile

Carla Torres-Fuentes, Rocio Muñoz-Alveal, Tamara Fernanda Cáceres Palma, Alejandra Fuentes-Garrido, Ninoschka Troncoso, Javiera Vera-Ceballos, David Flaig-Lobos, Valentina De La Fuente, Magdalena Cuevas-Troncoso, Gustavo Moraga-Cid, Carola Muñoz-Montesino,

Poster - 210186

Utilizing PPE for the detection of environmental chronic wasting disease prions

Lauren Wolfrath, Gage Rowden, Qi Yuan, Marc Schwabenlander, Diana Karwan, Jason Bartz, Tiffany Wolf, Peter Larsen,

Poster - 210218

Recent findings of scrapie protective genotypes in Iceland supported by case-control studies in Icelandic scrapie flocks.

Stefania Thorgeirsdottir, Eva Hauksdóttir, Karólína Elísabetardóttir, Gesine Lühken, Eyþór Einarsson, Vilhjálmur Svansson,

Poster - 210247

Regional distribution of prion protein gene polymorphisms identifies considerable susceptibility to infection with chronic wasting disease

W. David Walter, Alberto Fameli, Jessie Edson, Krysten Schuler, Chris Rosenberry,

Poster - 210285

Chronic wasting disease vaccination reduces shedding of prions in urine and feces

Hanaa Ahmed-Hassan, Dalia Abdelaziz, Yo-Ching Cheng, Kevin Low, Shirely Phan, Byron Kruger, Chimone Stefni Dalton, Maria Arifin, Sabine Gilch, Hermann Schätzl,

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