Natural Products As An Inspiration For Ovarian Cancer Therapies
Invited Lecture (IL)
Biodiversity and Natural Products
Date and time:
19:00 to 19:35 on 11/10/2021
: Natural products have inspired many therapies, including a number of those used to treat cancer. The seminar will focus on a class of compounds called phyllanthusmins, which were originally isolated from Phyllanthus poilanei Beille in Vietnam. Phyllanthusmins will be discussed as late stage autophagy inhibitors in ovarian cancer. The studies will cover strategies to define the biological target and mechanism of action for this interesting set of compounds.
University of Illinois at Chicago
JOANNA E BURDETTE
Professor in the Department of Pharmaceutical Sciences. In 2014, she was promoted to Associate Dean for Research. Her research has helped to develop three-dimensional models of the fallopian tube to define early events responsible for ovarian cancer formation. She is interested in the use of botanicals as a novel source of compounds that activate progesterone receptor signaling. She is also actively screening natural products for anti-cancer activity with a focus on ovarian cancer. She has been the recipient of the Liz Tilberis Scholar Award from the Ovarian Cancer Research Fund and was named the UIC Rising Star in the basic life sciences in 2013 and the UIC Distinguished Researcher in life sciences in 2020.
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